Pfizer Inc
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Registered: 4-22-2010
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![[*]](images/xp/default_icon.gif) posted on 7-20-2010 at 03:02 PM |
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In Vivo Pharmacologist (Metabolic disease or oncology)-Principal Scientist
In Vivo Pharmacologist (Metabolic disease)-Principal Scientist
Job Description
The mission of the Oligonucleotide Therapeutics Unit of Pfizer is to develop nucleic acid-based therapeutics for treating cancer or metabolic
diseases. Join a broad-based team of scientists to help make this a reality.
We are seeking a highly motivated, talented and innovative Scientist/Principal Scientist to join our biology team in developing technologies for
nucleic acid-based therapeutics. The ideal candidate will participate in team efforts to discover and develop nucleic acid-based therapeutics for the
treatment of metabolic disease and cancer.
Summary of Key Responsibilities:
- Working with external collaborators or in house resources, identify and/or develop appropriate project-specific animal models of human disease
(cancer and metabolic disease). The candidate would also manage the execution of in vivo studies evaluating our compounds using translational and
pharmacodynamic approaches to prioritize compounds.
- Provide in vivo pharmacology expertise to project teams during the discovery and development phases of projects.
- Design and implement cell-based and ex vivo studies to support the translation of in vitro data to preclinical models.
- Strong commitment to collaboration and working within a project team
Minimum requirements:
- Ph.D. and postdoctoral training or equivalent in the Biological Sciences with an emphasis in metabolic disease.
- Strong knowledge and experimental in vivo biology skills. This includes the development/establishment of in vivo animal disease models as well as
interpretation of the results. Strong animal surgery skills (primarily mouse and rat) and animal handling skills a must.
- Hands-on experience with microscopy, complex cell based bottomays, ELISAs, Western blots, cell culture, and basic biochemical skills required
as well as retroviral vector construction, siRNA and shRNA, Taqman and other advanced molecular skills.
- Ability to multi-tasks and participate in several projects simultaneously is a must.
- Effective communication skills (written and oral) and ability to articulate scientific results
- Strong commitment to collaboration and working within a project team
- Experience in advanced in vivo imaging techniques and immunohistochemistry a plus.
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color,
religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with
all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of
the Immigration and Nationality Act.
All applicants must have authorization to work for Pfizer in the U.S. In certain circumstances it may be advantageous to Pfizer to support the
application(s) for temporary visa clbottomification and/or sponsor applications for permanent residence so that a foreign national colleague
can accept or remain in a work bottomignment in the U. S. For certain clbottomes of temporary visas, the resulting work authorization
may be specific to Pfizer and the specific job and/or work site.
Pfizer may at its business discretion decide to or refrain from obtaining, maintaining and/or extending the temporary visa status and/or sponsoring a
colleague for permanent residency and /or employment eligibility, considering factors such as availability of qualified U.S. workers and the
colleague's long-term prospects for securing lawful permanent residence, among other reasons.
Employment applicants requiring immigration sponsorship must disclose, when initial application for employment is made, whether or not they are
legally authorized to work for Pfizer in the U.S. and, if so, whether that authorization permits them to work in the job they seek. In no case should
Pfizer's support of a colleague's temporary visa application or sponsorship of a colleague for permanent residence be construed to guarantee success
of that application or amend or otherwise invalidate the "at-will" employment relationship between the colleague and Pfizer.
Throughout our 153 years, a legacy of caring for others has been at the heart of everything we do at Pfizer. This commitment is no less important when
it comes to our employees. Pfizer wants to ensure that employees have resources to help them develop and succeed both in their careers and personal
lives. One way we can achieve this is through our comprehensive benefits program, which offers employees and their eligible dependents the variety and
flexibility to help address their needs at different stages in life.
Pfizer Inc: Working together for a healthier world
Founded in 1849, Pfizer is the world's premier biopharmaceutical company taking new approaches to better health. We discover, develop, manufacture and
deliver quality, safe and effective prescription medicines to treat and help prevent disease for both people and animals. We also partner with
healthcare providers, governments and local communities around the world to expand access to our medicines and to provide better quality health care
and health system support. At Pfizer, colleagues in more than 90 countries work every day to help people stay happier and healthier longer and to
reduce the human and economic burden of disease worldwide.
HOW TO APPLY:
Please E-mail your resume and requirements to:
R0744477408550@posttrak.arbita.net
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